Artificial Intelligence in Tumor Microenvironment Research: Hype, Hope, or Both?
Artificial Intelligence in Tumor Microenvironment
Keywords:
Artificial Intelligence, Tumor Microenvironment, Deep LearningAbstract
Tumor microenvironment (TME) is a dynamic and heterogeneous niche, which comprises of tumor cells, immune influx, stromal components and extracellular matrix fragments. Its space and molecular complexity pose a significant challenge to the conventional methods of analysis. The artificial intelligence (AI) can learn trends in big amounts of data which is the solution to this complexity. AI models can identify hidden morphological data, multi-omics, and clinical outcomes and thus provide a systems-level understanding of the TME. The integration of digital pathology results and AI is promising in predicting the presence of immune cells and patient prognosis, suggesting an indispensable role of AI in the future of cancer biology.
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